Human fall flat igg5/23/2023 In the United States it is unusual for any patient to show positive reactions to more than 1 of the arboviral antigens, although Western equine encephalitis and Eastern equine encephalitis antigens will show a noticeable cross-reactivity. Results from a single serum specimen can differentiate early (acute) infection from past infection with immunity if IgM is positive (suggests acute infection).Ī 4-fold or greater rise in IgG antibody titer in acute and convalescent sera indicate recent infection. Single serum specimen IgG greater than or equal to 1:10 indicates exposure to the virus. IgM class antibody is also reliably detected within 1 to 3 weeks of onset, peaking and rapidly declining within 3 months. In patients infected with this virus, IgG antibody is generally detectable within 1 to 3 weeks of onset, peaking within 1 to 2 months, and declining slowly thereafter.
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